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By Kate Kelland LONDON (Reuters) - GlaxoSmithKline said on Thursday it is applying for regulatory approval for the world's first vaccine against malaria, designed for children in Africa. The British drugmaker said the shot, called RTS,S, is intended exclusively for use outside the European Union but will be evaluated by the European Medicines Agency (EMA) in collaboration with the World Health Organisation (WHO). Malaria, a mosquito-borne parasitic disease, kills more than 600,000 people a year, mainly babies in the poorest parts of sub-Saharan Africa. Yet hopes that RTS,S would be the final answer to wiping out malaria were dampened when results from a final-stage trial in babies aged six to 12 weeks showed the shot provided only modest protection, reducing episodes of the disease by 30 percent compared to immunisation with a control vaccine.
By Hamid Ould Ahmed ALGIERS (Reuters) - An Air Algerie flight en route from Ouagadougou in Burkina Faso to Algiers is missing with 110 passengers on board, almost half of them French citizens, officials said on Thursday. There were no clear indications of what might of happened to the flight en route north to Algiers, but Burkino Faso Transport Minister Jean Bertin Ouedrago said the aircraft asked to change route at 0138 GMT (2138 ET) because of a storm in the area. Niger security sources said planes were flying over the border region with Mali to search for the flight. Algeria's state news agency APS said authorities lost contact with flight AH 5017 an hour after it took off from Burkina Faso, but other officials gave differing accounts of the times of contact, adding to confusion about the fate of the flight and where it might be.