LOS ANGELES (AP) — Ladies will continue to drive the feature lineup at the 2014 Sundance Film Festival as Robert Redford's independent-cinema fair celebrates its 30th anniversary next month in Park City, Utah.
A drug used to treat advanced breast and colorectal cancers has been linked to sometimes fatal skin reactions in patients, its Swiss manufacturer and Canadian health officials said. Xeloda, which treats advanced cancer after complete surgical removal, can cause "severe skin reactions," Health Canada said in a statement. It said patients had reported severe skin reactions, such as the life-threatening skin condition known as Stevens–Johnson Syndrome or toxic epidermal necrolysis. The signs and symptoms of this hypersensitivity include flu-like symptoms, fever, itchy skin, mouth sores, as well as painful, red or purplish skin rash that spreads and blisters, causing the top of the skin to shed, along with eye burning, itching and discharge.
DENVER (AP) — The jet stream hunkered to the south Wednesday, promising to bring nearly a week of temperatures that could dip to minus 20 or worse in the northern midsection of the country, and forcing much of the rest of the nation to deal with unexpectedly cool temperatures. In Minnesota, the cold has forced Salvation Army bell ringers inside and canceled holiday parties, while dense, cold air sunk into Rocky Mountain valleys and kept some lower elevations freezing in the West.